Survival Analysis

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​​Goals:

Construct parametric and non-parametric estimates of survival functions, compare two or more survival functions, estimate and interpret Cox proportional hazards model parameters

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Techniques presented:

Survival Analysis Techniques (Descriptive Analysis, Survival Curves, Univariate and Multivariate Analysis)

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Tutorials:

​Practical exercises are planned for each of the topics covered.

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Prerequisites: 

Attending the TSC course or having knowledge of the topics it contains is preparatory. It is advisable to attend the REG course.

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Subjects:

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Survival databases: characteristics

• Random variables of survival; the censoring

• Create a data set for survival analysis

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Descriptive analysis of survival

• The calculation of the median follow-up

• Calculation of median survival

• Calculation of rates

• Risk functions

• survival functions

• Construct survival curves

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Univariate analysis

• Kaplan-Meier Method (Product Limit)

• Actuarial method (Life-table)

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Multivariate analysis

• Cox's proportional hazards model

• Cox model with time-dependent variables

• Compare survival curves

• Hypothesis tests

• The Log-Rank test (Mantel-Haenzel)

• Stratified Cox models